What Are Cannabis Salves and Which Brands Offer the Best Relief

Cannabis salves have become increasingly popular as a natural remedy for localized pain, inflammation, and skin conditions. These topical products, infused with cannabinoids like CBD (cannabidiol) and THC (tetrahydrocannabinol), offer targeted relief without the psychoactive effects typically associated with cannabis. Whether you’re dealing with arthritis, sore muscles, or dry skin, salves provide a plant-based alternative to over-the-counter creams and prescription ointments.

What Are Cannabis Salves?

Cannabis salves are semi-solid topicals—typically waxy or balm-like in texture—made by infusing cannabis extract into a base of oils, waxes, and sometimes essential oils. Unlike edibles or vape products, salves are designed for external use only and interact with the body’s endocannabinoid system through the skin. Because they do not enter the bloodstream, salves won’t cause a “high,” even if they contain THC.

The main cannabinoids used in these products are:

  • CBD – known for its anti-inflammatory and analgesic properties.
  • THC – also has pain-relieving effects and can aid with muscle spasms and nerve pain when applied topically.
  • CBG, CBN, and other minor cannabinoids – increasingly featured for specialized benefits.

Many users report relief from chronic pain, muscle soreness, eczema, psoriasis, and even post-surgical scars. However, while clinical research is still evolving, a 2020 study published in Current Pharmaceutical Biotechnology supports the anti-inflammatory and analgesic effects of topical cannabinoids, making them promising for therapeutic use.

What Makes a Good Cannabis Salve?

High-quality salves should be made with full-spectrum or broad-spectrum cannabis extracts, organic carrier oils (like coconut or olive oil), and natural ingredients. Brands that use third-party testing, sustainable practices, and transparent labeling tend to stand out.

Top Cannabis Salve Brands in 2025

1. Papa & Barkley Releaf Balm

This California-based brand is a gold standard in cannabis topicals. Papa & Barkley’s Releaf Balm is infused with a 1:3 THC to CBD ratio, making it ideal for deep tissue relief. It features ingredients like eucalyptus, tea tree oil, and beeswax—free from solvents and chemicals. It’s especially popular among athletes and arthritis patients.

Pros: Fast absorption, strong effect, clean ingredients
Available in: Legal cannabis dispensaries in CA, CO, and select states

2. Mary’s Medicinals Muscle Freeze

Mary’s Medicinals offers a soothing, menthol-infused CBD and THC blend known as Muscle Freeze. Designed for quick, cooling relief, it’s a go-to for muscle spasms and sports recovery. The transdermal formula allows for deeper skin penetration compared to traditional salves.

Pros: Rapid cooling sensation, transdermal formula
Available in: Licensed dispensaries in multiple states, including Florida and Nevada

3. Khus + Khus Sen Face & Body CBD Balm

This luxury botanical brand focuses on high-end skincare with wellness in mind. Their Sen balm contains 200mg of full-spectrum CBD in a base of Ayurvedic herbs and oils. Ideal for dry skin and mild irritation, it’s a favorite in the clean beauty space.

Pros: Luxurious feel, clean beauty certified
Available online and in wellness boutiques nationwide

4. Lazarus Naturals Full Spectrum CBD Balm

For those looking for a cost-effective, high-potency option, Lazarus Naturals offers a 1,000mg CBD balm made with organic mango butter and beeswax. It’s fragrance-free, which is great for sensitive users.

Pros: Affordable, effective, and third-party tested
Available online nationwide

To Wrap Up

Cannabis salves offer a non-intoxicating, effective way to manage localized pain and inflammation. While more research is needed to fully understand their long-term benefits, current user experiences and early clinical findings are promising. Always consult with a healthcare provider, especially if you’re managing chronic conditions or using other medications.